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Research Highlights

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Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death

SARS-CoV-2 spike protein induces cognitive deficit and anxiety-like behavior in mouse via non-cell autonomous hippocampal neuronal death

Prof. Sung Joong Lee

Professor Sungjoong Lee's research team in the School of Dentistry revealed that the cause of cognitive and emotional disorders in COVID-19 patients was the neuronal cell death in the hippocampus by the 'spike protein' in SARS-CoV-2.

Comparative analysis of the oral microbiome of burning mouth syndrome patients

Comparative analysis of the oral microbiome of burning mouth syndrome patients

Prof. Gehoon Chung, Prof, Ji Woon Park, Prof. Bumjo Oh

The joint research team led by Professor Ji Woon Park and Professor Gehoon Chung in the School of Dentistry and Professor Bumjo Oh in the College of Medicine presented research results that identified the link between the burning mouth syndrome and oral microbiome.

Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction

Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann-Pick Type C disease phenotypes via autophagy induction

Prof. Kyung-Sun Kang

Professor Kyung-Sun Kang's research team in the College of Veterinary Medicine presented a development and mechanism for a new target protein in SAHA and HNHA, which inhibit HDAC, that ameliorates Niemann‐Pick Type C disease.

Hydrogel-based strong and fast actuators by electroosmotic turgor pressure

Hydrogel-based strong and fast actuators by electroosmotic turgor pressure

Prof. Jeong-yun Sun & Prof. Ho-young Kim

A research team led by Sun, Jeong-Yun of the Department of Materials Science and Engineering and Kim, Ho-Young of the Department of Mechanical Engineering announced that they have developed hydrogel actuators that can produce enough strength to break bricks in a short time.

The C. elegans Regulatory Factor X (RFX) DAF-19M module : a shift from general ciliogenesis to cell-specific ciliary and behavioral specialization

The C. elegans Regulatory Factor X (RFX) DAF-19M module : a shift from general ciliogenesis to cell-specific ciliary and behavioral specialization

Prof. Junho Lee

Professor Junho Lee's research team in the School of Biological Sciences announced that they have identified the modulator that determines the characteristics of IL2 neurons, which play an important role in the hitchhiking behavior of C. elegans.

CPNE7 regenerates periodontal ligament via TAU-mediated alignment and cementum attachment protein-mediated attachment

CPNE7 regenerates periodontal ligament via TAU-mediated alignment and cementum attachment protein-mediated attachment

Prof. Joo-Cheol Park

Professor Joo-Cheol Park's research team in the School of dentistry revealed that the CPNE7 protein excavated from the dental epithelium during tooth development regulates the organization and arrangement of periodontal ligament cells.

Multi-Bandgap Monolithic Metal Nanowire Percolation Network Sensor Integration by Reversible Selective Laser-Induced Redox

Multi-Bandgap Monolithic Metal Nanowire Percolation Network Sensor Integration by Reversible Selective Laser-Induced Redox

Prof. Seung Hwan Ko

Professor Seung Hwan Ko's research team in the Department of Mechanical Engineering announced that they have developed a technology that creates device by precisely controling the properties of metal nanowire thin film.

Coupling structural evolution and oxygen-redox electrochemistry in layered transition metal oxides

Coupling structural evolution and oxygen-redox electrochemistry in layered transition metal oxides

Prof. Kisuk Kang

Professor Kisuk Kang’s research team at the Department of Materials Science and Engineering announced that they have succeeded in figuring out the mechanism of oxygen/redox-dependent degradation and newly designing the anode materials for the next-generation sodium-ion battery.

Soft multi-modal thermoelectric skin for dual functionality of underwater energy harvesting and thermoregulation

Soft multi-modal thermoelectric skin for dual functionality of underwater energy harvesting and thermoregulation

Prof. Seung Hwan Ko

Professor Seunghwan Ko's research team in the Department of Mechanical Engineering announced that they have developed an electronic skin that can regulate body temperature and generate electricity by itself according to the user's needs in the water.

Homeostatic serum IgE is secreted by plasma cells in the thymus and enhances mast cell survival

Homeostatic serum IgE is secreted by plasma cells in the thymus and enhances mast cell survival

Prof. You Jeong Lee

Professor Lee Yu-jeong's research team at the College of Pharmacy announced that they have identified the origin of the unknown E-type immunoglobulin and its role in allergic diseases.

Surface Nanopatterned Shape Memory Alloy (SMA)-Based Photosensitive Artificial Muscle

Surface Nanopatterned Shape Memory Alloy (SMA)-Based Photosensitive Artificial Muscle

Prof. Sung-Hoon Ahn, Prof. Heui Jae Pahk

A joint research team led by Professor Ahn Sung-hoon and Park Hee-jae of the Department of Mechanical Engineering announced that they have developed a light-sensitive artificial muscle that mimics the muscle of the iris that contracts when stimulated by light.

FAM167A is a key molecule to induce BCR-ABL-independent TKI resistance in CML via noncanonical NF-kB signaling activation

FAM167A is a key molecule to induce BCR-ABL-independent TKI resistance in CML via noncanonical NF-kB signaling activation

Prof. Sung-Gyoo Park

Professor Park Seong-gyu's research team at the College of Pharmacy has uncovered a new causative mechanism that causes Gleevec resistance of chronic myeloid leukemia.