This study present a strategy for targeting GPCRs for hard tissue regeneration by promoting the biomineralization of mesenchymal stromal cells. The discovered GPCR-targeting drugs revealed potent regenerative effects in both tooth and bone defects.

Interferon regulatory factor 1 (IRF1) is a transcriptional regulator conventionally associated with immunomodulation. Recent molecular analyses mapping DNA binding sites of IRF1 have suggested its potential function in DNA repair.

Nitrous oxide (or nitrous oxide, N2O) is a major greenhouse gas, along with carbon dioxide (CO2) and methane (CH4), and is about 300 times more potent than CO2.

In order to flower in the appropriate season, plants monitor light and temperature changes and alter downstream pathways that regulate florigen genes such as Arabidopsis (Arabidopsis thaliana) FLOWERING LOCUS T (FT).

Chondrosarcomas represent the second most common primary bone malignancy. Despite the vulnerability of chondrosarcoma cells to nicotinamide adenine dinucleotide (NAD) depletion, targeting the NAD+ synthesis pathway remains challenging due to broad implications in biological processes.

The phytohormone salicylic acid (SA) triggers transcriptional reprogramming that leads to SA-induced immunity in plants. NPR1 is an SA receptor and master transcriptional regulator in SA-triggered transcriptional reprogramming.

The highly pathogenic avian influenza H5 2.3.4.4 and 2.3.2.1c subclades have distinct antigenic properties and are responsible for the majority of human infections.

In recent years, there has been considerable interest in the therapeutic targeting of tumor-associated macrophages (TAMs) to modulate the tumor microenvironment (TME), resulting in antitumoral phenotypes.

Prof. Moon Seong Kang and his research team have developed an evaluation method for future flood probability, addressing an agricultural reservoir watershed and the hydraulic structures within.

Professor Sung-Gyoo Park's research team from the College of Pharmacy at SNU has discovered WDR44 variants that induce human ciliopathy through international collaborative work with researchers from 8 nations.

Chub mackerels (Scomber japonicus) are a migratory marine fish widely distributed in the Indo-Pacific Ocean.

Malaria is still endemic in South Korea. However, limited information is available on the current Anopheles breeding sites and the occurrence of insecticide resistance-associated genetic mutations and their distribution needed to control the malaria vector efficiently.