Research Research Highlights
Research Highlights
Research Highlights
Research Highlights
Research Highlights 미리보기

First to Uncover What Happens to mRNA Vaccines in the Body
Prof. V. Narry Kim
A Korean research team has, for the first time globally, elucidated the intracellular mechanisms by which mRNA vaccines function, marking a significant advancement in RNA-based therapeutics.
Research Highlights Board

Targeted and Logical Discovery of Piperazic Acid-Bearing Natural Products Based on Genomic and Spectroscopic Signatures
Prof. Dong-Chan Oh
A targeted and logical discovery method was devised for natural products containing piperazic acid (Piz), which is biosynthesized from ornithine by l-ornithine N-hydroxylase (KtzI) and N–N bond formation enzyme (KtzT). Genomic signature-based screening of a bacterial DNA library (2020 strains) using polymerase chain reaction (PCR) primers targeting ktzT identified 62 strains (3.1%).

Agrivoltaic system designing for sustainability and smart farming: Agronomic aspects and design criteria with safety assessment
Prof. Won Choi
An agrivoltaic system (AVS) offers a potential strategy for meeting global demands for renewable energy and sustainability by integrating photovoltaics and agriculture.

SNU have reported the formation of zero-twisted fully commensurate van der Waals structure
Prof. Gwan-Hyoung Lee
Professor Gwan-Hyoung Lee's research team from the Department of Materials Science and Engineering at SNU has reported the thermally induced atomic reconstruction into fully commensurate structure of randomly stacked 2D layers.

Palmitic acid aggravates liver cancer progression
Prof. Yang-Sook Chun
A research team led by Professor Yang-Sook Chun from the Department of Physiology & Biomedical Sciences at SNU has uncovered the molecular mechanism of palmitoylation-driven lipid reprogramming in liver cancer cells.

Adenosine monophosphate enhances callus regeneration competence for de novo plant organogenesis
Prof. Pil Joon Seo
Many crop plants have genetic barriers to de novo organogenesis during tissue culture. Therefore, exogenous application of metabolites and/or small molecules that promote cell fate transition in tissue culture-recalcitrant species could be key solution for current bottlenecks.

Exploring the Diverse Landscape of Biaryl-Containing Peptides Generated by Cytochrome P450 Macrocylcases
Prof. Dong-Chan Oh, and Seokhee Kim
Cytochrome P450 enzymes (P450s) catalyze diverse oxidative cross-coupling reactions between aromatic substrates in natural product biosynthesis.

Proposing New Evolutionary Connections from 214 Million Predicted Protein Structure Database
Prof. Martin Steinegger
Prof. Steinegger‘s team from the Department of Biological Science at SNU has unlocked the gate to the large predicted protein structure AlphaFold Database by clustering the 214M structures into 2M shape-groups, revealing putative homology in prokaryotic species to human immune-related proteins.

Novel pathological mechanism of Alzheimer’s disease uncovered
Prof. Min Jae Lee
Professor Lee's group and colleagues from the Department of Biomedical Sciences at SNU College of Medicine have identified a novel pathological mechanism of Alzheimer’s disease, which opens first-in-class therapeutic strategies.

Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance
Prof. Sung Joong Lee
Social hierarchy is established as an outcome of individual social behaviors, such as dominance behavior during long-term interactions with others. Astrocytes are implicated in optimizing the balance between excitatory and inhibitory (E/I) neuronal activity, which may influence social behavior.

A whole-genome reference panel of 14,393 individuals for East Asian populations accelerates discovery of rare functional variants
Prof. Jong-il Kim
Underrepresentation of non-European (EUR) populations hinders growth of global precision medicine. Resources such as imputation reference panels that match the study population are necessary to find low-frequency variants with substantial effects.

Triple spiral arms of a triple protostar system imaged in molecular lines
Prof. Jeong-Eun Lee
Most stars form in multiple-star systems. For a better understanding of their formation processes, it is important to resolve the individual protostellar components and the surrounding envelope and disk material at the earliest possible formation epoch, because the formation history can be lost in a few orbital timescales.

New-generation geostationary satellite reveals widespread midday depression in dryland photosynthesis during 2020 western U.S. heatwave
Prof. Youngryel Ryu
Emerging new-generation geostationary satellites have broadened the scope for studying the diurnal cycle of ecosystem functions. We exploit observations from the Geostationary Operational Environmental Satellite-R series to examine the effect of a severe U.S. heatwave in 2020 on the diurnal variations of ecosystem photosynthesis.