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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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Seasonal variability of ocean circulation near the Dotson Ice Shelf, Antarctica

Seasonal variability of ocean circulation near the Dotson Ice Shelf, Antarctica

Prof. Yang-ki Cho

A joint research team led by Professor Yang-ki Cho of the Department of Earth and Environmental Sciences revealed, for the first time in the world, the seasonal variability of seawater that melts the ice shelf of the Amundsen Sea in West Antarctica, which is most vulnerable to global warming.

Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics

Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics

Prof. Jae Bum Kim

Professor Jae-beom Kim's joint research team from the Department of Life Sciences announced that they have identified the effect of stem cell groups in visceral fat and subcutaneous fat on various functional changes in adipose tissue.

In operando visualization of redox flow battery in membrane-free microfluidic platform

In operando visualization of redox flow battery in membrane-free microfluidic platform

Prof. Sung Jae Kim

A joint research team led by Professor Sungjae Kim and Kisuk Kang announced that they have implemented a redox flow battery system that allows electrolytes to exchange ions without a membrane.

Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease

Multimodal brain and retinal imaging of dopaminergic degeneration in Parkinson disease

Prof. Jee-Young Lee

Professor Jee-Young Lee’s research team at the College of Medicine announced the achievements of the research which was conducted over 10 years on multimodal brain and retinal imaging as a biomarker for Parkinson disease.

Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Selenophosphate synthetase 1 deficiency exacerbates osteoarthritis by dysregulating redox homeostasis

Prof. Jin-Hong Kim

Professor Jinhong Kim and Byeongjae Lee of the Department of Life Sciences researched the joint protective efficacy of selenium metabolism and presented a clue for the treatment strategy for degenerative arthritis based on this.

Structural basis of neuropeptide Y signaling through Y1 receptor

Structural basis of neuropeptide Y signaling through Y1 receptor

Prof. Hee-Jung Choi

Professor Hee-Jeong Choi's research team at the Department of Life Sciences announced that they have identified for the first time the cryogenic electron microscope structure of the neuropeptide Y1 receptor, which can be used as a target for the treatment of obesity.

Obesity at early adulthood increases risk of gastric cancer from the Health Examinees-Gem (HEXA-G) study

Obesity at early adulthood increases risk of gastric cancer from the Health Examinees-Gem (HEXA-G) study

Prof. Daehee Kang

Professor Kang Dae-hee's research team at the College of Medicine announced the results of a significant association between obesity and future gastric cancer risk in young adults aged 35 years.

Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

Prof. Seung-Yong Jeong & Ja-Lok Ku

The research team led by Professor Ja-Rok Koo and Seung-Yong Jeong of the Department of Medicine revealed that colon cancer is very heterogeneous not only in the genome but also in the transcriptome stage.

Estimating Risk of Cardiovascular Disease Among Long-Term Colorectal Cancer Survivors: A Nationwide Cohort Study

Estimating Risk of Cardiovascular Disease Among Long-Term Colorectal Cancer Survivors: A Nationwide Cohort Study

Prof. Sang Min Park

Professor Sangmin Park's research team at the Department of Family Medicine announced that they have developed a model for estimating the risk of cardiovascular disease in long-term colorectal cancer survivors.

In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy

In vivo delivery of CRISPR-Cas9 using lipid nanoparticles enables antithrombin gene editing for sustainable hemophilia A and B therapy

Prof. Su Cheong Yeom

The joint research team of Professor Yeom Soo-Cheong of the International Graduate School of Agricultural Technology presented a research result that can treat hemophilia by efficient and long-term control of antithrombin, a target gene for hemophilia treatment.

Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis

Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis

Prof. Won-Woo LEE

Professor Won-woo Lee's research team at the College of Medicine identified the mechanism of enhancing the inflammatory response and suggested a new possibility for controlling the immune response of patients with chronic inflammatory diseases such as rheumatoid arthritis.

Identification of Sex Pheromone Components of Korean Dioryctria abietella (Lepidoptera: Pyralidae) Population and Synergism of Pheromone and Pine Cone Volatile Blends

Identification of Sex Pheromone Components of Korean Dioryctria abietella (Lepidoptera: Pyralidae) Population and Synergism of Pheromone and Pine Cone Volatile Blends

Prof. Il-Kwon Park

Professor Il-Kwon Park's research team at the Department of Agriculture, Forestry and Biological Resources announced that they had succeeded in identifying and artificially synthesizing the sex pheromone components of Korean Dioryctria abietella (Lepidoptera: Pyralidae) population, which causes enormous damage to the endangered Korean fir's (Abies koreana) cone.