While the neuropathological characteristics of Niemann-Pick disease type C (NPC) result in a fatal diagnosis, the development of clinically available therapeutic agent remains a challenge. Here we propose graphene quantum dots (GQDs) as a potential candidate for the impaired functions in NPC in vivo. In addition to the...

Telomeres are part of a highly refined system for maintaining the stability of linear chromosomes.

L1 retrotransposons can pose a threat to genome integrity. The host has evolved to restrict L1 replication.

Here, we report that physically mixed H-Y zeolite effectively protects vanadium active sites by trapping ABS in micropores.

Intensified anthropogenic activities and high levels of energy consumption in cities have led to an increase in emissions of CO2 and air pollutants, impacting air quality and calling for better measures to monitor and reduce emissions. This study assesses the emission characteristics of cities in the Northern Hemispher...

Coupled transcription and translation processes in bacteria cause indiscriminate translation of intact and truncated messenger RNAs, inevitably generating nonfunctional polypeptides.

In most bacteria, efficient use of carbohydrates is primarily mediated by the phosphoenolpyruvate (PEP):carbohydrate phosphotransferase system (PTS), which concomitantly phosphorylates the substrates during import.

Nucleation in atomic crystallization remains poorly understood, despite advances in classical nucleation theory.

Metal chalcogenide magic-sized nanoclusters have shown intriguing photophysical and chemical properties, yet ambient instability has hampered their extensive applications. Here we explore the periodic assembly of these nanoscale building blocks through organic linkers to overcome such limitations and further boost thei...

RNA–protein interaction is central to post-transcriptional gene regulation. Identification of RNA-binding proteins relies mainly on UV-induced crosslinking (UVX) followed by the enrichment of RNA–protein conjugates and LC-MS/MS analysis.

Identifying and interpreting pleiotropic loci is essential to understanding the shared etiology among diseases and complex traits.

The practical operation of wearable robots requires intuitive, compact, yet reliable control interfaces.