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Research Highlights

Research Highlights /

Research Highlights

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Temporally Distinct 3D Multi-Omic Dynamics in the Developing Human Brain

Prof. Dong-Sung Lee

Professor Dongsung Lee from the College of Medicine at SNU, in collaboration with researchers at UCLA and UCSF, has published a paper in Nature, being the first in the world to study epigenomic changes, including the three-dimensional genome structure and DNA methylation, during human brain development from the fetal stage to adulthood at the single-cell level, using the single-nucleus methyl-3C technology they developed.

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Novel laser-thermal mechanism realizes ultra-fast construction of PDMS devices

Novel laser-thermal mechanism realizes ultra-fast construction of PDMS devices

Prof. Seung Hwan Ko

Researchers at Seoul National University in South Korea reported the development of new laser-based polydimethylsiloxane (PDMS) processing mechanism that enables the mask-less direct fabrication of various PDMS structures.

Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer’s disease

Rhizolutin, a novel 7/10/6‐tricyclic dilactone, dissociates misfolded protein aggregates and reduces apoptosis/inflammation associated with Alzheimer’s disease

Prof. Dong-Chan Oh

Rhizolutin ( 1 ) was discovered as a natural product of ginseng‐rhizospheric Streptomyces sp. WON17. Its structure featured an unprecedented 7/10/6‐tricyclic dilactone carbon skeleton composed of dimethylcyclodecatriene flanked by a 7‐membered and a 6‐membered lactone ring based on spectroscopic analysis. During an unb...

A Large‐Scale Array of Ordered Graphene‐Sandwiched Chambers for Quantitative Liquid‐Phase Transmission Electron Microscopy

A Large‐Scale Array of Ordered Graphene‐Sandwiched Chambers for Quantitative Liquid‐Phase Transmission Electron Microscopy

Prof. Jungwon Park

Liquid‐phase transmission electron microscopy (TEM) offers a real‐time microscopic observation of the nanometer scale for understanding the underlying mechanisms of the growth, etching, and interactions of colloidal nanoparticles. Despite such unique capability and potential application in diverse fields of analytical ...

Monolithic digital patterning of polydimethylsiloxane with successive laser pyrolysis

Monolithic digital patterning of polydimethylsiloxane with successive laser pyrolysis

Prof. Seung Hwan Ko & Prof. Noo Li Jeon

The patterning of polydimethylsiloxane (PDMS) into complex two-dimensional (2D) or 3D shapes is a crucial step for diverse applications based on soft lithography. Nevertheless, mould replication that incorporates time-consuming and costly photolithography processes still remains the dominant technology in the field. He...

Quantum distance and anomalous Landau levels of flat bands

Quantum distance and anomalous Landau levels of flat bands

Prof. Bohm-Jung Yang

Semiclassical quantization of electronic states under a magnetic field, as proposed by Onsager, describes not only the Landau level spectrum but also the geometric responses of metals under a magnetic field. Even in graphene with relativistic energy dispersion, Onsager’s rule correctly describes the π Berry phase, as w...

Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis

Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis

Prof. Ho Jae Han

Hyperglycemia in diabetes mellitus (DM) patients is a causative factor for amyloidogenesis and induces neuropathological changes, such as impaired neuronal integrity, neurodegeneration, and cognitive impairment.

Resource-Efficient Topological Fault-Tolerant Quantum Computation with Hybrid Entanglement of Light

Resource-Efficient Topological Fault-Tolerant Quantum Computation with Hybrid Entanglement of Light

Prof. Hyunseok Jeong

We propose an all-linear-optical scheme to ballistically generate a cluster state for measurement-based topological fault-tolerant quantum computation using hybrid photonic qubits entangled in a continuous-discrete domain.

Topological Hyperbolic Lattices

Topological Hyperbolic Lattices

Prof. Namkyoo Park

Non-Euclidean geometry, discovered by negating Euclid’s parallel postulate, has been of considerable interest in mathematics and related fields for the description of geographical coordinates, Internet infrastructures, and the general theory of relativity.

Water Passivation of Perovskite Nanocrystals Enables Air‐Stable Intrinsically Stretchable Color‐Conversion Layers for Stretchable Displays

Water Passivation of Perovskite Nanocrystals Enables Air‐Stable Intrinsically Stretchable Color‐Conversion Layers for Stretchable Displays

Prof. Tae-Woo Lee

Conventional organic light‐emitting devices without an encapsulation layer are susceptible to degradation when exposed to air, so realization of air‐stable intrinsically‐stretchable display is a great challenge because the protection of the devices against penetration of moisture and oxygen is even more difficult under stretching.

Coherent many-body exciton in van der Waals antiferromagnet NiPS3

Coherent many-body exciton in van der Waals antiferromagnet NiPS3

Prof. Je-Geun Park

An exciton is the bosonic quasiparticle of electron–hole pairs bound by the Coulomb interaction. Bose–Einstein condensation of this exciton state has long been the subject of speculation in various model systems, and examples have been found more recently in optical lattices and two-dimensional materials.

Ionic spiderwebs enable cleaning contamination on itself, sensing approaching targets, capturing and releasing those targets

Ionic spiderwebs enable cleaning contamination on itself, sensing approaching targets, capturing and releasing those targets

Prof. Ho-young Kim, Prof. Jeong Yun Sun

Spiders use adhesive, stretchable, and translucent webs to capture their prey. However, sustaining the capturing capability of these webs can be challenging because the webs inevitably invite contamination, thus reducing its adhesion force. To overcome these challenges, spiders have developed strategies of using webs t...

Proton-transfer-induced 3D/2D hybrid perovskites suppress ion migration and reduce luminance overshoot

Proton-transfer-induced 3D/2D hybrid perovskites suppress ion migration and reduce luminance overshoot

Prof. Tae-Woo Lee, Department of Materials Science and Engineering

Perovskite light-emitting diodes (PeLEDs) based on three-dimensional (3D) polycrystalline perovskites suffer from ion migration, which causes overshoot of luminance over time during operation and reduces its operational lifetime. Here, we demonstrate 3D/2D hybrid PeLEDs with extremely reduced luminance overshoot and 21...