Subject: High-throughput analysis of proteins using tandem mass spectrometry and statistical methods

Speaker: CHOI Hyungwon (Professor, National University of Singapore)

Date: December 22 (Thu), 11 am.

Place: College of Phamacy (Bldg. #20, Room 203)

Contact: Tel. 02-880-7844

Summary
Advances in tandem mass spectrometry have allowed high throughput characterization of proteins in biological samples. In this talk we review the field of mass spectrometry-based shotgun proteomics and the statistical methods employed in the data analysis. Topics include false discovery rate estimation in peptide/protein identification and Bayesian hierarchical models for differential protein expression analysis under the restriction of extremely limited sample size.